Biomedical Health Research Centre

The Leeds Teaching Hospitals NHS Trust

Recently funded STRF Projects

Dr Georgia Mavria

Regulation of Rho GTPases in cancer angiogenesis


Date awarded: April 2010

Total value of grant: £224,000

Duration: 3 years

Funding Body: YCR

Summary: 

We are interested to understand the molecular mechanisms that regulate the formation of new blood vessels in tumours. Rho GTPases regulate key processes undergone by endothelial cells during angiogenesis such as cell migration and cell-cell junction formation. Research funded by this YCR project grant will reveal how Rho proteins required for angiogenesis such as CDC42 are controlled by upstream regulators during tumour angiogenesis

Dr Mavria’s profile