Our
people
Professor Stephen Smye
Title
BHRC Director, Director of the NIHR Comprehensive Clinical Research Network and Director of the NIHR CLAHRC for Leeds, Bradford and York
S.W.Smye@leeds.ac.uk
Phone
0113 3926519 or contact Pauline Binnie (PA) on 0113 392337
Address
Leeds Teaching Hospitals NHS Trust
34 Hyde Terrace
Leeds
LS2 9LN
BHRC Role
- BHRC Management Team member
- BHRC Executive Team member
- BHRC SSAC member
Research Interests
- Mathematical modelling in medicine (including chemotherapy, MRI)
- Electromagnetic techniques in medicine (including electroporation)
About
Professor Stephen Smye is Director of Research and Development at the Leeds Teaching Hospitals NHS Trust and Director of the NIHR Comprehensive Clinical Research Network.
Professor Smye is a physicist by profession, with degrees from Cambridge University, Imperial College, and Leeds University. He is also a member of the NIHR Advisory Board and of the Royal College of Physicians’ Standing Committee on Academic Medicine. He was made an Honorary Fellow of the College in 2005.
He has worked in nuclear medicine and bioengineering, and was President of the Institute of Physics and Engineering in Medicine (2001-2003), which comprises over 3000 physicists, engineers and technologists working within the Health Service, academia and industry, in the UK and overseas.
He aims to encourage high quality translational research and innovation, including supporting good working relationships between physical scientists and clinicians at both a local and national level. He is engaged in a number of grant-funded research programmes jointly with Leeds University, notably in mathematical modelling of physiological processes and is an Honorary Professor of Medical Physics and Health Research in the Faculty of Medicine, Dentistry and Health at Leeds University.
He was co-applicant on a recent successful application to the Wellcome Trust and EPSRC for £11m to create a major medical engineering centre with a focus on tissue engineering and regenerative medicine. He is also a collaborator on an National Institute of Health Research (NIHR) award to create a Health Technology Cooperative (Devices for Dignity), led by Professor Wendy Tindale of the Sheffield Teaching Hospitals Foundation Trust.
He has also been involved in the development of NHS policy for Research and Development, and is a member of the MHRA Medical Technology Forum. He was previously Vice Chair of the Northern and Yorkshire Regional Research Capacity Committee, a member of the Department of Health’s Research Governance steering group, and a member of the Science Council. He was a co-applicant on the successful joint bid from Leeds and London for the UK Coordinating Centre for Clinical Research Networks and was a member of the steering group for the UKCRN. He was a member of the Researcher Development Awards panel for the National Institute of Health Research’s Research Capacity Development programme.
Collaboration
He has played a key role in encouraging high quality translational research and innovation, including supporting good working relationships between physical scientists and clinicians at both a local and national level.
These collaborations currently entail research programmes in a number of areas including;
- modelling drug transport in tumours (with Dr Roger Philips, University of Bradford, Professor Brian Sleeman, Department of Applied Mathematics and Dr Pam Jones, Leeds Institute of Molecular Medicine),
- electroporation (with Professor Peter Olmsted, Physics Department),
- the development of a novel in-vivo electroporation technique (with Dr Martin Robinson, University of York and Dr Tony Evans, Division of Medical Physics) and
- measurement and modelling of the gravid uterus electro-hysterograms (with Professor Arun Holden, Faculty of Biological Sciences and Mr Nigel Simpson Faculty of Medicine and Health).
Previous work has included modelling the variation of blood gases in ventilated neonates, optimising the delivery of drug aerosols, the development of electrical techniques for the measurement of hydration status, the development and use of mathematical models to measure dialysis efficiency and clot formation, the use of TeraHertz radiation to measure tissue properties and application of neural networks to clinical datasets. Funders include NIHR, EPSRC, Yorkshire Cancer Research, MRC, Leukaemia Research Fund, SPARKS, NHS R&D.
Good working relationships between scientists and clinicians have been an important feature of each of these programmes.
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