Our
people
Professor Philip Kocienski
Title
Professor of Organic Chemistry
P.J.Kocienski@leeds.ac.uk
Phone
0113 3436400 or contact Gail Cole (PA) on 0113 3436555
Address
G27 School of Chemistry
University of Leeds
Leeds
LS2 9JT
BHRC Role
BHRC SSAC member
Research Interests
- Organometallic chemistry
- Synthesis
- Natural products
- Antibiotics
- Vitamins
- Antifungal agents
- Antitumour agents, immunosuppressants
- Antiviral agents
- Antiinflammatory agents
- Enzyme inhibitors
About
Professor Kocienski is a graduate of Brown University and became a lecturer at the University of Leeds in 1979, and Professor of Chemistry at the University of Southampton in 1985. He was was Regius Professor of Chemistry at the University of Glasgow from 1997 to 2000. In 2000 he returned to Leeds as Professor and Head of the Department of Organic Chemistry and then Head of the School of Chemistry.
Philip’s research concerns the development of new synthetic methods and their application to the synthesis of biologically active natural products. A conspicuous example is the sulfone-based olefination (the Julia–Kocienski reaction) which was developed for the synthesis of herboxidiene and rapamycin. It is now widely used in fragment linkage reactions in complex natural prodyuct synthesis. His interests also embrace various aspects of organometallic chemistry such as the use of planar chiral cationic π-allylmetal complexes for the stereospecific appendage of chains to rings and the stereoselective synthesis of trisubstituted alkenes via copper(I)-mediated1,2-metallate rearrangements which features in our syntheses of D-erythro-sphingosine and manoalide.
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