Biomedical Health Research Centre

The Leeds Teaching Hospitals NHS Trust

Our
people

Dr Steven Johnson

Title


Senior Translational Research Fellow (Nanostructured Electronic Devices for Biomolecular Sensing & Analysis)

Email


S.D.Johnson@leeds.ac.uk

Phone


0113 3431061

Address


Room 4.63
School of Electronic and Electrical Engineering
University of Leeds
Leeds
LS2 9JT

BHRC Role


STRF

Research Interests

  • Biosensors
  • Nanoelectronics
  • Aptamers

About


Steve Johnson graduated from the University of York, UK, with an BEng. in Electronic Engineering and received his PhD from the same institution with a thesis on the study of miniature electron optic devices and field emission from nanometer-scale cathodes. His research interests and activities have subsequently become increasingly multi-disciplinary and for the past four years, he has been investigating hybrid bio-nanoelectronic systems in which nanoelectronic devices are integrated with molecular and biomolecular components. A significant outcome of this research was the demonstration of a miniaturized electronic, label-free, and array-format protein chip which for the first time, employs synthetically engineered proteins (peptide aptamers) to recognise specific protein isoforms. As STRF within the BHRC, his research activities focus on the fabrication and development of such hybrid bio-nanoelectronic sensors and their application for example in biological investigation, in drug discovery and in point-of-care diagnostics.

S. Johnson, D. Evans, S. Laurenson, A. G. Davies, P. K. Ferrigno, C. Wälti, Surface immobilised peptide aptamers as probe molecules for protein detection, Anal. Chem. 80, 978 (2008)

D. Evans, S. Johnson, S. Laurenson, A. G. Davies, P. K. Ferrigno, C. Wälti, Label-free electrochemical sensing of peptide aptamer-protein interactions using micro-electrode arrays, Journal of Biology, 7:3 (2008)

Collaboration


Paul Ko Ferrigno (LIMM)

(peptide aptamers as novel probe molecules for biomolecular analysis)

Related Links


Bioelectronics Research Group