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Dr Robin Bon
Title
Senior Translational Research Fellow (Medicinal Chemistry linked to Cardiovascular Disease)Phone
0113 34(33196)Address
2.88 School of Chemistry
University of Leeds
Leeds
LS2 9JT
BHRC Role
STRF
Research Interests
- Synthetic Chemistry
- Medicinal Chemistry
- Chemical Biology
- Chemical Genetics
- Biology Oriented Synthesis
About
Robin Bon studied chemistry at Utrecht University, the Hogeschool van Amsterdam and the Hogeschool van Utrecht. His graduation research (performed under supervision of Prof. Dr. Henk Hiemstra and Dr. Jan van Maarseveen at the University of Amsterdam) involved the synthesis of bridged ketopiperazines using N-acyliminium ion chemistry. Robin obtained his PhD in January 2007 from the Department of Chemistry at the Vrije Universiteit Amsterdam (supervisors Prof. Dr. Marinus Groen and Prof. Dr. Romano Orru). His thesis describes the development of new multicomponent reactions and their application in the synthesis of N-heterocyclic carbene complexes and Nutlin analogues. In August 2006, Robin started as a post-doctoral fellow in the lab of Prof. Dr. Herbert Waldmann at the Max Planck Institute of Molecular Physiology in Dortmund, Germany. His research, which focused on the design, synthesis and evaluation of selective inhibitors of the enzyme Rab geranylgeranyltransferase, was financially supported by the Alexander von Humboldt Foundation.
Robin’s current research interests include synthesis and screening of compound libraries, design, synthesis and evaluation of enzyme inhibitors and development of tools for biochemical assays.
Collaboration
During PhD research:
Prof. Dr. Matthias Bickelhaupt/Dr. Marcel Swart (Vrije Universiteit Amsterdam)
Prof. Dr. Alexander Dömling (University of Pittsburgh)
Prof. Dr. Ekkehardt Hahn/Dr. Mareike Jahnke (Westfälische Wilhelms-Universität Münster)
During post-doctoral research:
Prof. Dr. Roger Goody/Dr. Wulf Blankenfeldt (MPI Dortmund)
Prof. Dr. Kirill Alexandrov (The University of Queensland, Australia)
Dr. Axel Choidas/Dr. Peter Nussbaumer (Lead Discovery Center of the Max Planck Society, Dortmund)
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