Our
people
Dr Richard Foster
Title
Medicinal Chemistry and Chemical Biology (MCCB) Technology Group Leader
R.Foster@leeds.ac.uk
Phone
0113 3435759
Address
School of Chemistry
University of Leeds
Leeds
LS2 9JT
BHRC Role
Technology Group Leader
Research Interests
- Medicinal chemistry
- Chemical biology
- Hit identification
- Hit-to-lead
- Lead optimisation
- Combinatorial chemistry
- Drug design
- High-throughput screening
- Synthetic chemistry
- Molecular modelling
- IP management
About
Richard recently joined the BHRC from Industry where he worked for 10 years as a project manager for a CRO servicing the pharmaceutical pre-clinical research sector. In this position he was responsible for leading research programs aimed at delivery of candidate compounds meeting pre-defined criteria for eventual progression to IND status. Richard was educated at the University of Leeds, receiving a BSc in Chemistry and a PhD in Organic Chemistry.
Richard’s research interests lie in the design, synthesis and optimisation of small molecules for therapeutic application or their use in the elucidation of biological function. By combining tools and techniques in high-throughput screening, combinatorial chemistry, medicinal chemistry, and computational chemistry the aim is to identify and optimise targeted small molecules as key modulators of specific biological function. These multidisciplinary projects form part of collaborative frameworks with scientists and clinicians from a variety of backgrounds both within the university and from outside.
Collaboration
Richard is currently working on a number of collaborations with researchers across the University of Leeds from a number of groups, including the Institute of Molecular and Cell Biology and Division of Cardiovascular and Diabetes Research. Most of these collaborations are aimed at identification and optimisation of small molecule inhibitors for progression as possible therapeutics or to better understand the role of the target in the disease state.
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