Biomedical Health Research Centre

The Leeds Teaching Hospitals NHS Trust

Our
people

Dr Paul Beales

Title

Senior Translational Research Fellow (Medicinal Chemistry for Targeted Drug Delivery)

Email

p.a.beales@leeds.ac.uk

Phone

0113 34(39101)

Address

Centre for Molecular Nanoscience,

Chemistry Building 4.10b,

University of Leeds,

Leeds, LS2 9JT

Research Interests

  • Biomolecular self-assembly
  • Membrane biophysics
  • Biomolecular adhesion and molecular recognition
  • Bottom-up synthetic biology
  • Biomimetic materials
  • Biological soft matter
  • Bionanotechnology
  • Medical applications of soft biomaterials

About

  • Postdoctoral Research Associate under Prof. T. Kyle Vanderlick, Department of Chemical & Environmental Engineering, Yale University (2008-2010)
  • Postdoctoral Research Associate under Prof. T. Kyle Vanderlick, Department of Chemical Engineering, Princeton University (2005-2008)
  • Ph.D. under the supervision of Prof. Wilson C.K. Poon and Stefan U. Egelhaaf, School of Physics, University of Edinburgh (2001-2005). Thesis: Domain formation in binary lipid vesicles studied by fluorescence microscopy.
  • Undergraduate degree: M.Phys. in physics from the University of Edinburgh (1997-2001).


Paul’s current research interests include, but are not limited to, applications of nucleic acid-functionalised membranes, novel strategies for targeted drug delivery, therapeutic encapsulation in novel lipid-based systems, fundamental interactions between artificial cells and drug delivery systems (efficiency of intra-cellular transport) or nanoparticles (potential nanotoxicity), and development of more sophisticated artificial cellular models.

Collaboration

Past & present collaborators:

  • Prof. Kyle Vanderlick (Yale University)
  • Prof. Corey Wilson (Yale University)
  • Prof. Fred Sigworth (Yale University)
  • Prof. John Groves (Princeton University)
  • Prof. Wilson Poon (University of Edinburgh)
  • Prof. Stefan Egelhaaf (Heinrich-Heine-Universität)
  • Prof. Mike Cates (University of Edinburgh)
  • Prof. Vernita Gordon (University of Texas at Austin)
  • Prof. Peter Olmsted (University of Leeds)
  • Prof. Fred MacKintosh (Vrije University)
  • Prof. John Seddon (Imperial College London)
  • Dr. Lindsay Sawyer (University of Edinburgh)