Our
people
Dr Mihaela Lorger
Title
Senior Translational Research Fellow (Breast cancer and brain metastasis)Phone
0113 34(38449)Address
Section of Experimental OncologyCancer Research UK BuildingLeeds Institute of Molecular MedicineSt. James’s University HospitalBeckett StreetLeeds LS9 7TFBHRC Role
STRF
Research Interests
- Breast cancer
- Brain metastasis
- Cell and gene therapy
About
Dr. Lorger obtained her Ph.D. degree in biology from the Darmstadt University of Technology, Germany. During her postdoctoral studies at the University of Zurich, Switzerland and at The Scripps Research Institute, La Jolla, CA, USA she focused on breast cancer progression and metastasis.
The goal of our current research is to pinpoint molecular mechanisms leading to breast cancer metastasis. We are particularly interested in the role of tumour microenvironment in the brain at the cellular and molecular level, with a main focus on the identification of potential therapeutic targets. We are also developing a cell-based approach for the delivery of therapeutic agents to metastatic brain lesions. This approach aims at overcoming current limitations in drug delivery to the central nervous system.
Collaboration
- Dr. Heiko Wurdak, STRF, LIMM
- Dr. Stephanie Cherqui, Assistant Professor, The Scripps Research Institute, La Jolla, CA
- Dr. Brunhilde Felding-Habermann, Associate Professor, The Scripps Research Institute, La Jolla, CA
Grants Awarded
IDEA Award, California Breast Cancer Research Program (2010)
