Dr Georgia Mavria

Title

Senior Translational Research Fellow. Signal Transduction and Cancer Angiogenesis Group Leader

Email

G.Mavria@leeds.ac.uk

Address

Leeds Institute of Molecular Medicine
Section of Oncology and Clinical Research
St James’s University Hospital 
Beckett Street
Leeds
LS9 7TF 

BHRC Role

STRF

Research Interests

• Cancer Angiogenesis
• Rho GTPases
• Endothelial-tumour cell interactions

About

Dr Mavria’s group is working to elucidate the precise molecular mechanisms that underpin  the process of new vessel growth in tumours. They are particularly interested in novel Rho and Rho-related signalling pathways activated during angiogenesis. Positive or negative regulators of Rho family members may constitute therapeutic targets for anti-angiogenic tharapies in cancers.

Collaboration

Professor Chris Marshall, Institute of Cancer Research, London

Grants Awarded

CR-UK project grant:  Identification of Rho Family GTPases and regulatory proteins required for angiogenesis (2007-2010)

YCR grant: Regulation of Rho GTPases in cancer angiogenesis (awarded April 2010)