MCCB
Group Capabilities
The MCCB group has core capabilities in a number of areas for which bioactive molecules may be identified and optimised as therapeutics or deployed as tools to understand biological mechanism:
Medicinal chemistry
- Hit identification
- Hit-to-lead
Chemical Biology
- Chemical diagnostics and probes
- Imaging agents
- Affinity chromatography
Computational chemistry and virtual drug design
- Ligand-and structure-based design
- Virtual screening
- De novo design
- Physicochemical and ADME property prediction
- Novel protein-protein inhibitor virtual libraries
High-throughput screening
- 20k member diverse lead-like library, including novel scaffolds based on diversity orientated synthesis
- Assay transfer
- Liquid handling robotics
- Data gathering and analysis
Targeted capabilities
- Modulators of protein-protein interactions

